OWNERSHIP PROFILE

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 139 684.66 110.09 47,487,779
Mutual Fund 209 293.95 51.55 22,236,532
Insider 4 6.45 0.86 372,793

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 62 47.69 7.71 3,325,245
Sellers 82 -82.22 12.69 -5,474,105
Net -- -34.53 4.98 -2,148,860

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 684.66 110.09 47,487,779
Top 10 Inst. 508.50 81.86 35,312,283
Top 20 Inst. 617.96 99.48 42,913,584
Top 50 Inst. 673.30 108.24 46,692,758

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 31 57.46 9.18 3,961,135
Aggressive Growth 1 0.01 -- 881
Core Growth 23 34.19 5.40 2,331,032
Growth 7 23.25 3.78 1,629,222
Income 4 31.56 5.08 2,192,980
Income Value 2 30.40 4.89 2,110,800
Yield 2 1.17 0.19 82,180
Index 19 104.12 16.77 7,233,070
Other 46 384.64 61.94 26,721,327
Broker Dealer 8 6.19 1.00 429,812
GARP 14 171.62 27.62 11,914,570
Hedge Fund 20 46.30 7.48 3,228,272
Sector Specific 1 29.49 4.75 2,048,147
Specialty 2 0.16 0.03 11,485
VC/Private Equi 1 130.88 21.07 9,089,041
Value 19 95.73 15.42 6,653,503
Core Value 18 94.11 15.16 6,540,550
Deep Value 1 1.63 0.26 112,953

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
New Enterprise Associates (NEA) 9,089,041 21.07 -- 9/30/18
Wellington Management Company, LLP 5,673,374 13.15 80,984 9/30/18
OppenheimerFunds, Inc. 4,422,132 10.25 1,460,938 9/30/18
T. Rowe Price Associates, Inc. 3,443,579 7.98 -3,929 9/30/18
BlackRock Institutional Trust Company, N.A. 2,661,432 6.17 48,332 9/30/18
Fidelity Management & Research Company 2,510,350 5.82 32,387 9/30/18
Redmile Group, LLC 2,048,147 4.75 18,800 9/30/18
Franklin Advisers, Inc. 2,016,325 4.67 -147,500 9/30/18
State Street Global Advisors (US) 1,756,353 4.07 -168,831 9/30/18
The Vanguard Group, Inc. 1,691,550 3.92 26,951 9/30/18
Jennison Associates LLC 1,498,808 3.47 -95,049 9/30/18
Fidelity Institutional Asset Management 1,291,133 2.99 8,500 9/30/18
Janus Henderson Investors 1,169,490 2.71 -15,040 9/30/18
Citadel LLC 850,069 1.97 -603,008 9/30/18
AXA Investment Managers UK Ltd. 725,818 1.68 112,879 9/30/18
Alyeska Investment Group, L.P. 450,133 1.04 -8,969 9/30/18
Northern Trust Investments, Inc. 415,099 0.96 27,902 9/30/18
GLG Partners LP 411,995 0.96 355,329 9/30/18
Ghost Tree Capital, LLC 400,000 0.93 -- 9/30/18
Dimensional Fund Advisors, L.P. 388,756 0.90 388,756 9/30/18
APG Asset Management 362,153 0.84 -17,423 6/30/18
Geode Capital Management, L.L.C. 354,611 0.82 29,299 9/30/18
King (Rachel K) 317,802 0.74 -- 3/23/18
RA Capital Management, LLC 253,547 0.59 -- 9/30/18
Sphera Funds Management Ltd. 251,013 0.58 11,080 9/30/18
Point72 Asset Management, L.P. 185,000 0.43 5,000 9/30/18
Jefferies LLC 170,695 0.40 170,695 9/30/18
Hudson Bay Capital Management LP 170,000 0.39 50,000 9/30/18
Thackray (Helen M) 148,615 0.34 -- 3/23/18
Nuveen LLC 134,618 0.31 -4,357 9/30/18
Allianz Global Investors U.S. LLC 118,448 0.27 118,448 9/30/18
BlackRock Investment Management, LLC 112,953 0.26 255 9/30/18
K2 Advisors L.L.C. 95,320 0.22 -- 10/31/18
BNY Mellon Asset Management 94,475 0.22 3,067 9/30/18
Magnani (John L) 80,638 0.19 -25,000 10/18/18
Asset Management One Co., Ltd. 80,097 0.19 80,097 7/31/17
Citi Investment Research (US) 78,983 0.18 19,569 9/30/18
Charles Schwab Investment Management, Inc. 76,385 0.18 2,363 9/30/18
Alps Advisors, Inc. 76,195 0.18 14,536 9/30/18
Goldman Sachs & Company, Inc. 75,691 0.18 53,952 9/30/18
TD Asset Management Inc. 72,672 0.17 3,500 9/30/18
Deutsche Asset Management Americas 61,154 0.14 -34,412 9/30/18
Schweizerische Nationalbank 59,200 0.14 -- 9/30/18
BlackRock Financial Management, Inc. 58,039 0.13 3,678 9/30/18
Morgan Stanley & Co. LLC 56,445 0.13 -15,676 9/30/18
California State Teachers Retirement System 51,796 0.12 345 9/30/18
Moore Capital Management, LP 50,000 0.12 -50,000 9/30/18
Lazard Asset Management, L.L.C. 48,359 0.11 48,359 9/30/18
BNY Mellon Asset Management North America Corporation 46,970 0.11 -- 9/30/18
New York State Common Retirement Fund 37,300 0.09 -- 9/30/18

* Insider values reflect direct beneficial ownership.

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